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Aloe vera () is a of the . It is widely distributed, and is considered an in many world regions.

An , it originates from the Arabian Peninsula, but also grows wild in tropical, semi-tropical, and arid climates around the world. It is cultivated for commercial products, mainly as a topical treatment used over centuries. The species is considered attractive for decorative purposes, and is often used indoors as a .

The leaves of Aloe vera contain significant amounts of the gel , which can be used for topical purposes. The leaves also contain , which is a compound. Aloe vera products are typically made from the gel.

Aloe vera acemannan may be used in skin lotions, , ointments and gels for minor burns, skin abrasions, insect bites, and .

Oral ingestion of aloe vera may cause acute abdominal pain and cramps, and if consumed chronically. It should not be used during pregnancy. Some people have to aloe when used on skin.


Etymology
The genus name is derived from the word alloeh, meaning "bitter and shiny substance" or from אוהלים ahalim, plural of אוהל ahal. The vera comes from verus meaning "true" in .


Common names
Common names use aloe with a region of its distribution, such as Chinese aloe, Cape aloe or aloe.


Taxonomy
The species has several synonyms: Aloe barbadensis Mill., Aloe indica Royle, Aloe perfoliata L. var. vera and Aloe vulgaris Lam. Some literature identifies the white-spotted form of Aloe vera as Aloe vera var. chinensis; and the spotted form of Aloe vera may be with A. massawana. The species was first described by in 1753 as Aloe perfoliata var. vera,Linnaeus, C. (1753). Species plantarum, exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas. Vol. 2 pp. i, 561–1200, 1–30,, i,. Holmiae Stockholm: Impensis Laurentii Salvii. and was described again in 1768 by Nicolaas Laurens Burman as Aloe vera in Flora Indica on 6 April and by as Aloe barbadensis some ten days after Burman in the Gardener's Dictionary.

Techniques based on comparison suggest Aloe vera is relatively closely related to , a species endemic to Yemen. Similar techniques, using DNA sequence comparison and inter simple sequence repeat profiling have also suggested it is closely related to , , Aloe scobinifolia, , and . With the exception of the South African species A. striata, these Aloe species are native to (Yemen), Somalia, and Sudan. The lack of obvious natural populations of the species has led some authors to suggest Aloe vera may be of hybrid origin.Jones WD, Sacamano C. (2000) Landscape Plants for Dry Regions: More Than 600 Species from Around the World. California Bill's Automotive Publishers. USA.


Description
Aloe vera is a stemless or very short-stemmed plant growing to tall, spreading by offsets.


Leaves
The leaves are thick and fleshy, green to grey-green, with some varieties showing white flecks on their upper and lower stem surfaces.Yates A. (2002) Yates Garden Guide. Harper Collins Australia The margin of the leaf is and has small white teeth.

Aloe vera leaves contain under study for possible bioactivity, such as , , , acetylated , polymannans, C-, , and other anthraquinones, such as and various .


Flowers
The flowers are produced in summer on a spike up to tall, each flower being pendulous, with a yellow tubular corolla long.
(2025). 9781740514347, Random House Publishers.
Random House Australia/


Roots
Like other Aloe species, Aloe vera forms arbuscular mycorrhiza, a root that allows the plant better access to mineral nutrients from the soil.


Distribution
Aloe vera is considered to be native only to the south-east Arabian Peninsula in the in north-eastern and eastern U.A.E. However, it has been widely cultivated around the world, and has become naturalized in North Africa, as well as Sudan and neighboring countries, along with the , , and . It has also naturalized in the region of Portugal, and in wild areas across Spain, especially in the region of Murcia.

The species was introduced to China and various parts of southern in the 17th century.Farooqi, A. A. and Sreeramu, B. S. (2001) Cultivation of Medicinal and Aromatic Crops. Orient Longman, India. . p. 25. It is widely naturalized elsewhere, occurring in arid, temperate, and tropical regions of temperate continents. The current distribution may be the result of cultivation. "Aloe vera (Linnaeus) Burman f., Fl. Indica. 83. 1768." in Flora of North America Vol. 26, p. 411


Cultivation
Aloe vera has been widely grown as an ornamental plant. The species is popular with modern gardeners as a topical and for its interesting flowers, form, and succulence. This succulence enables the species to survive in areas of low natural rainfall, making it ideal for rockeries and other low water-use gardens. The species is hardy in 8–11, and is intolerant of heavy frost and snow. The species is relatively resistant to most insect pests, though , , , and species may cause a decline in plant health. This plant has gained the Royal Horticultural Society's Award of Garden Merit.

In pots, the species requires well-drained, sandy potting soil, and bright, sunny conditions. Aloe plants can turn red from sunburn under too much direct sun, though gradual acclimation may help. The use of a good-quality commercial propagation mix or packaged "cacti and succulent mix" is recommended, as they allow good drainage. Terra cotta pots are preferable as they are porous. Potted plants should be allowed to completely dry before rewatering. When potted, aloes can become crowded with "pups" growing from the sides of the "mother plant". Plants that have become crowded can be divided and repotted to allow room for further growth, or the pups can be left with the mother plant. During winter, Aloe vera may become dormant, during which little moisture is required. In areas that receive frost or snow, the species is best kept indoors or in heated glasshouses.

There is large-scale agricultural production of Aloe vera in Australia, Cuba, the Dominican Republic, China, Mexico, India, Jamaica, Kenya, Tanzania, South Africa, Spain, and the United States, with much of the output going toward the cosmetics industry.


Uses
Two substances from Aloe vera – a clear and its yellow – are used to manufacture commercial products. Aloe gel typically is used to make topical medications for skin conditions, such as burns, wounds, frostbite, , , , and dry skin. Aloe latex is used individually or manufactured as a product with other ingredients to be ingested for relief of . Aloe latex may be obtained in a dried form called resin or as "aloe dried juice".

There is conflicting evidence regarding whether Aloe vera is effective as a treatment for wounds or burns. There is some evidence that topical use of aloe products might relieve symptoms of certain skin disorders, such as , , or , but topical application may cause an allergic reaction in some people.

Aloe vera is used commercially as an ingredient in , beverages, and some desserts, but at high or prolonged doses, ingesting aloe latex or whole leaf extract can be toxic. Use of topical aloe vera in small amounts is likely to be safe.


Topical medication and potential side effects
Aloe vera may be prepared as a , , soap or cosmetics product for use on skin as a topical medication. For people with to Aloe vera, skin reactions may include contact dermatitis with , difficulty with breathing, or swelling of the face, lips, tongue, or throat.


Dietary supplement
Aloin, a compound found in the semi-liquid latex of some Aloe species, was a common ingredient in over-the-counter (OTC) products in the United States until 2002 when the Food and Drug Administration banned it because manufacturers failed to provide the necessary safety data. Aloe vera has potential toxicity, with occurring at some dose levels both when ingested and when applied topically. Although toxicity may be less when aloin is removed by processing, Aloe vera ingested in high amounts may induce side effects, such as , or . Chronic ingestion of aloe (dose of 1 gram per day) may cause adverse effects, including , weight loss, and cardiac or kidney disorders.

Aloe vera juice is marketed to support the health of the digestive system, but there is neither scientific evidence nor regulatory approval for this claim. The extracts and quantities typically used for such purposes are associated with toxicity in a dose-dependent way.


Traditional medicine
Aloe vera is used in traditional medicine as a skin treatment. Early records of its use appear from the fourth millennium . It is also written of in the Juliana Anicia Codex of 512 CE.Reynolds, Tom (Ed.) (2004) Aloes: The genus Aloe (Medicinal and Aromatic Plants - Industrial Profiles. CRC Press.


Commodities
Aloe vera is used on where it is promoted as a moisturizer and anti-irritant to reduce chafing of the nose. Cosmetic companies commonly add sap or other derivatives from Aloe vera to products such as makeup, tissues, moisturizers, soaps, sunscreens, incense, shaving cream, or shampoos. A review of academic literature notes that its inclusion in many hygiene products is due to its "moisturizing emollient effect".


Toxicity
Orally ingested non-decolorized aloe vera leaf extract was listed by the California Office of Environmental Health Hazard Assessment among "chemicals known to the state to or reproductive toxicity", possibly resulting from the .

Since 2016, aloe vera whole leaf extract is classified as a possible human carcinogen (group 2B) by the International Agency for Research on Cancer.

Use of aloe vera on the skin is generally not associated with significant side effects. Oral ingestion of aloe vera is potentially toxic, and may cause and which in turn can decrease the absorption of drugs.


Interactions with prescribed drugs
Ingested aloe products may have adverse , such as those used to treat , , and -lowering agents (such as ), and , among others.


Gallery
File:Aloe vera leaf showing the gel (1).JPG|Leaf and inner gel File:Aloe vera gel.jpg|Gel used for File:Es Lidah Buaya.JPG| Es lidah buaya, an Indonesian Aloe vera iced drink File:Gelaloevera.JPG|Juice File:Cut Aloe Vera Leaf.jpg|Cut leaf File:Aloe vera cut leaf drawing1.jpg|Diagram of leaf: 1 Cuticle, 2 Chloroplast parenchym, 3 Inner tissue,  4 Vascular bundles File:Aloe Vera Buds.jpg|Buds File:Aloe Vera flower.jpg|Flower buds File:Aloe vera flower 2.jpg|Flowers File:AloeBluhendD2.JPG|Plants of different sizes File:A potted aloe vera plant.jpg|A potted plant File:Aloe plant bud.jpg|


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